Barrett's Esophagus Patient

Risk of chronic acid reflux, or GERD

Gastric reflux occurs when stomach acid or bile flows into the food pipe and irritates the lining. Acid reflux and heartburn more than twice a week may indicate GastroEsophageal Reflux Disease (GERD). Chronic acid reflux, or GERD, even after a Bariatric surgery, puts people at risk for Barrett’s esophagus.  It’s a change in the lining of the esophagus that, if left untreated, can lead to cancer.  If you have GERD or Barrett’s Esophagus, it is important to understand how Barrett’s develops, and the importance of a timely and accurate diagnosis so that prompt treatment can be delivered.

Barrett's Esophagus is a serious condition that affects the lining of the esophagus, it has no symptoms other than those experienced by those with acid reflux disease and, if left untreated, can lead to cancer of the esophagus.

Only a physician can determine if you have Barrett's Esophagus

This pre-cancerous condition does not occur with everyone experiencing acid reflux (GERD) or who has the previously noted symptoms or risk factors.

Patients should see their physician for an accurate diagnosis and treatment.

 Cellvizio Procedure

Waiting for Biopsy Results May Soon Become "a Thing of the Past"

Optical biopsy with new advance microscopic imaging Cellvizio technology enables doctors to examine tissue at the microscopic level during an endoscopic examination facilitating traditional tissue sampling and even potentially reducing the need for a separate and time consuming pathological evaluation. a Tissue sampling being the current method used by physicians to have the tissues assessed remotely by a Pathologist with various microscopic techniques.

As a physician examines a patient’s esophageal tissue using Cellvizio optical biopsy to check for Barrett’s Esophagus or dysplasia within Barrett’s Esophagus, he or she is provided with real-time images of the tissue that can help determine whether or not cancer is present at that time.b This way, trained physicians are able to make faster evaluations, which have the potential to result in quicker treatment of Barrett’s Esophagus and the problems associated with it.c 


How Cellvizio Works

Cellvizio performs microscopic imaging (optical biopsy) of esophageal tissue during an endoscopy to determine the presence of Barrett’s Esophagus and conditions such as cancer.  2,3,4,5

The procedure combines advanced imaging technology, endoscopy and ergonomics for ease of use and patient comfort.  Using a safe laser scanning imaging technology, the images created by Cellvizio are produced by optically penetrating thin layers of tissue.  There is no removal of tissue samples for a separate evaluation. These images provide physicians with information which can assist in making a diagnosis during the endoscopy.  

 The images below are representative of different phases of changes in the lining of the tissue of the esophagus that can be seen with Cellvizio1.

GERD Barrett's Esophagus Cellvizio  1. Kiesslich R. et al. In Vivo Histology of Barrett’s Esophagus and Associated Neoplasia by Confocal Laser Endomicroscopy. Clinical Gastro and Hepatology, 2006 

Diagnosing Barrett’s Esophagus and Cancer Faster

Because Cellvizio optical biopsy enables the visualization of tissues at the cellular level while an endoscopic examination is taking place, it provides information that assists the physicians in potentially “seeing cancer faster”, as it is seeing in real time. The System’s ability to facilitate cancer detection is dependent upon the amount of tissue inspected and the physician’s ability to correctly interpret the images obtained.  

The benefits of this technology may include:

  • immediate tissue and cell characterization results
  • real-time decision making for your physician
  • improved therapeutic options for patients
  • faster intervention to treat cancer faster 

Patient Stories

The words of patients say it best. Their stories are really the story of Barrett's Esophagus, how it is diagnosed with optical biopsy and treated. Read all the featured stories and watch patients describe their journey through Barrett's Esophagus      Learn More

Watch the video to learn more about how using Cellvizio optical biopsy provides real-time images and diagnostic information for a faster diagnosis: